Medicament storage, dispensing, and administration system and method

ABSTRACT

Various exemplary embodiments relate to an electronic device for dispensing a medicament. The electronic device may include a medicament storage case or an electronic medicament device. The medicament storage case includes: a door moveable between an open position and a closed position; a lock moveable between a locked position where the lock maintains the door in the closed position and an unlocked position where the lock allows the door to move to the open position; a medicament dispensing device containing medication; an input device located on an external surface of the storage case activatable by a user; a communication unit configured to initiate a two-way communication between the user and a remote access control center upon activation of the input device and configured to receive an access signal from the remote access control center; and an actuator responsive to the access signal to move the lock to the open position upon receipt of the communication from the remote access control center. The electronic medicament device includes a reservoir configured to store an amount of medication, an administration component for administering the medication to a patient, and a processor communicatively connected to a memory.

TECHNICAL FIELD

Various exemplary embodiments disclosed herein relate generally tostorage, distribution, and administration of medicaments.

BACKGROUND

Some people suffer from medical conditions such as severe allergies thatmay result in anaphylaxis. Anaphylaxis may be treated by administrationof epinephrine. Patients may be prescribed an auto-injector ofepinephrine to treat sudden anaphylaxis.

Anaphylaxis, however, often leads to an emergency situation whereinepinephrine or other medication should be administered as soon aspossible to prevent loss of life or other complications. It cannot beguaranteed that in all such situations, a patient entering anaphylacticshock is currently in possession of their prescribed auto-injector orhas been previously prescribed an auto-injector at all. Further, in somecases, such as when the patient is a child, administration should besupervised or otherwise guided to prevent misuse. Again, in an emergencysituation, a supervisor knowledgeable in the administration of themedication may not be available.

SUMMARY

In light of the present need for various contingency plans in theadministration of epinephrine and other medications, a brief summary ofvarious exemplary embodiments is presented. Some simplifications andomissions may be made in the following summary, which is intended tohighlight and introduce some aspects of the various exemplaryembodiments, but not to limit the scope of the invention. Detaileddescriptions of a preferred exemplary embodiment adequate to allow thoseof ordinary skill in the art to make and use the inventive concepts willfollow in later sections.

Various exemplary embodiments relate to a medicament storage case. Themedicament storage case includes: a door moveable between an openposition and a closed position; a lock moveable between a lockedposition where the lock maintains the door in the closed position and anunlocked position where the lock allows the door to move to the openposition; a medicament dispensing device containing medication; an inputdevice located on the storage case activatable by a user; acommunication unit configured to initiate a two-way communicationbetween the user and a remote access control center upon activation ofthe input device and configured to receive an access signal from theremote access control center; and an actuator responsive to the accesssignal to move the lock to the open position upon receipt of thecommunication from the remote access control center.

In various embodiments, the medicament storage case further includes aglobal positioning system (GPS) receiver configured to generate locationinformation for the storage case, wherein the communication unit isfurther configured to communicate the location information to emergencyresponders.

In various embodiments, the medicament storage case is mounted to awall.

In various embodiments, the user is not required to provide anyidentification or authorization credential.

In various embodiments, the medicament storage case receives informationand generates a local access signal.

In various embodiments, the communication unit includes a connection toan internet.

In various embodiments, the medicament storage case further includes aplurality of medicament locks that each retain a medicament dispensingdevice and the access signal unlocks a single medicament lock.

In various embodiments, the medicament storage case reads an expirationdate from the medicament device.

In various embodiments, the medicament dispensing device is anauto-injector.

Various embodiments relate to system including: a lockable medicamentstorage container comprising a medicament dispensing device and acommunication unit; and a central access control terminal in two-waycommunication with the lockable medicament storage container andconfigured to remotely unlock the medicament storage container based oninput from a human operator.

In various embodiments, the lockable medicament storage containerfurther comprises a global positioning system (GPS) receiver configuredto generate location information, wherein the communication unit isconfigured to transmit the location information to an emergency responsesystem.

In various embodiments, the lockable medicament storage container isoperable by an unregistered user.

Various embodiments relate to a method of unlocking a medicament storagecase. The method includes: receiving, at a central access controlterminal, a communication initiation from a remote medicament storagecase; facilitating a two-way communication between a user of the remotemedicament storage case and an operator of the central access controlterminal; determining whether the medicament storage case contains amedicament dispensing device for treating a condition of the user or apatient; and transmitting an access signal to the medicament storagecase to unlock a portion of the medicament storage case containing themedicament dispensing device for treating the condition of the user orthe patient.

In various embodiments, the method further includes: receiving a GPSlocation from the medicament storage case; and forwarding the GPSlocation information to an emergency responder in the vicinity of themedicament storage case.

In various embodiments, the method further includes: providinginstructions for using the medicament dispensing device.

In various embodiments, the instructions are at least one of audioinstructions and video instructions.

In various embodiments, the method further includes performing a remotemedical diagnosis of the patient based on the two-way communication.

In various embodiments, the method further includes: accessing a medicalrecord of the patient. Various exemplary embodiments relate to anelectronic medicament device including: a reservoir configured to storean amount of medication; an administration component for administeringthe medication to a patient; and a processor communicatively connectedto a memory. In various embodiments, the administration component is anauto-injector.

Various embodiments are described wherein the electronic medicamentdevice additionally includes at least one of a display, a speaker, acommunications interface, a GPS device, and an ID tag to be read byanother device. In such embodiments, the processor may be configured tocommunicate the expiration of the medication via the display, provideaudio administration instructions via the speaker, or communicate theoccurrence of events (such as expiration or administration) to a remotedevice. In some embodiments, the processor may be configured to controlthe amount of medication administered to a patient based on informationsuch as a locally-stored or remotely-retrieved patient record or patientinformation manually input into the electronic medicament device such asgender, age, and/or weight.

BRIEF DESCRIPTION OF THE DRAWINGS

In order to better understand various exemplary embodiments, referenceis made to the accompanying drawings, wherein:

FIG. 1 illustrates an exemplary medicament storage case;

FIG. 2 illustrates a schematic diagram of the components of a medicamentstorage case;

FIG. 3 illustrates an exemplary electronic medicament device;

FIG. 4 illustrates an exemplary network environment for a medicamentstorage case and electronic medicament device;

FIG. 5 illustrates a flowchart showing an exemplary method of providingremote access to a medicament; and

FIG. 6 illustrates a flowchart showing an exemplary method of monitoringa medicament.

DETAILED DESCRIPTION

Referring now to the drawings, in which like numerals refer to likecomponents or steps, there are disclosed broad aspects of variousexemplary embodiments.

FIG. 1 illustrates an exemplary medicament storage case 100. Themedicament storage case 100 may be used to provide a secure storagelocation for emergency medications such as, for example, auto-injectorsof epinephrine. Medicament storage case 100 may be placed in a locationwhere emergency medications may be needed. For example, medicamentstorage case 100 may be located in a school, church, child carefacility, mass transit facility (such as an airport or train station),or vehicle. The medicament storage case 100 may be secured to a wall orother immovable object using any known securing hardware to preventtheft and tampering. The medicament storage case 100 may be accessed byan authorized person or patient to obtain prescription medication forthe patient. The medicament storage case 100 may also facilitatecommunication with a central control center where an operator mayremotely provide access to the medication. Medicament storage case 100may include a door 102, hinges 104, lock 106, medicaments 120,medicament locks 122, camera 130, microphone 132, speaker 133, display134, card reader 135, and wireless reader 140. Although not shown, themedicament storage case 100 may include various additional electroniccomponents such as, for example, a processor, memory, and networkinterface, as will be described in greater detail below with respect toFIG. 2.

Door 102 is secured to case 100 by hinges 104. Hinges 104 allow door 102to move between an open position and a closed position. Hinges 104 maybe resistant to tampering. For example, hinges 104 may be mounted to aninternal surface of case 100 such that access to hinges 104 is preventedwhen case 100 is closed and locked. Alternatively, door 102 may be asliding door secured to case 100 by rails or other known door, window,or access panel arrangement. In another alternative, door 102 may bemanufactured from glass or other clear frangible material that may bebroken in case of emergency. Breaking the frangible material may resultin actuation of the storage case 100, including actuation of thecommunication unit 230.

Lock 106 may include any lock for mechanically securing the door 102 ina closed position. For example, lock 106 may be of the dead bolt varietyand engage a recess on door 102. Lock 106 may include an actuator formoving the lock 106 between a locked position and an unlocked position.For example, lock 106 may include a solenoid that moves lock 106 whenenergized. The actuator may include an authentication circuit thatverifies an access signal. If the authentication circuit verifies anaccess signal, the actuator may move lock 106 to an unlocked position.If an incorrect access signal is received, the lock 106 may remain in alocked position. Alternatively, the lock 106 may not verify an accesssignal and instead may be controlled by another component, such as aprocessor.

Medicaments 120 may include one or more medicaments for treatingemergency or other medical conditions. In various exemplary embodiments,medicaments 120 may be auto-injectors for administering a dose ofepinephrine. Other suitable medicaments may include, but are not limitedto, adrenergic agonists, antihistamines (e.g. diphenhydramine,hydroxyzine); H2 receptor antagonists (e.g. cimetidine, ranitidine, andfamotidine), bronchodilators (e.g. albuterol), corticosteroids (e.g.prednisone), positive inotropic agents (e.g. glucagon and insulin),opioid antagonists (e.g. naloxone), and other medicaments for use inemergency conditions (e.g. N-acetylcysteine). Suitable auto-injectorsand associated devices and method are described by U.S. Pat. Nos.4,031,893; 4,394,863, 4,484,910; 4,640,686; 4,678,461; 4,795,433;4,832,682; 5,085,641; 5,092,843; 5,102,393; 5,354,286; 7,449,012; and8,048,035, all of which are hereby incorporated by reference in theirentireties for all purposes. Medicaments 120 may also include electronicauto-injectors described in further detail below with reference FIG. 3.Medicaments 120 may treat different conditions or provide differentdoses of medication. For example, medicament 120 a may provide a largerdose than that provided by medicament 120 b or may include a differentmedication from that included in medicament 120 b. It will be apparentthat, while two medicaments 120 are illustrated, a medicament storagecase 100 may include a greater or fewer number of medicaments.

Medicament locks 122 may be additional locks that secure individualmedicaments within case 100. Each medicament lock 122 may include anactuator that moves the medicament lock 122 into an unlocked position.As shown, medicament locks 122 may include a ring or cable that securethe medicament 120 to case 100. Alternatively, medicament locks 122 mayinclude locking doors or drawers securing medicaments 120. Medicamentlocks 122 may require separate access conditions. For example, a firstauthorized patient may be able to access medicament 120 a, but notmedicament 120 b, while a second authorized patient may be provided withaccess only to medicament 120 b. Such access may be determined bylocally- or remotely-stored prescription information or other patientrecords. Authorized emergency caregivers, such as medical professionalsor on-site medical staff, may be provided with access to all medicaments120 stored in the storage case 100.

Camera 130 may be a digital camera capable of recording video. As willbe described in further detail below, camera 130 may be used to providelive video to an operator located at a remote facility. The video may beused to diagnose a patient or determine whether a request for themedicament is authentic. Camera 130 may be mounted to case 130 such thatit is movable. For example, camera 130 may be attached with a hinge orpivot such that camera 130 may be manually moved to capture video of asubject. In various embodiments, the camera 130 and/or supportingstructures may be provided with electrically operable mechanicaldevices, such as servo motors, such that the processor and/or remoteoperator may alter the position or orientation of the camera 130. Invarious embodiments, camera 130 may be mounted in a removable mannersuch that a subject out of view of case 100 may be viewed. Camera 130may include a lock to prevent its removal. Camera 130 may be unlockedremotely by an operator.

Microphone 132 may record audio input. Microphone 132 may be usedinstead of, or in addition to, camera 130 to communicate with a remoteoperator. Microphone 132 may be integrated with camera 130.

Speaker 133 may provide audio output. Speaker 133 may be used tocommunicate with a remote operator and/or may play pre-recorded messagesstored at case 100. For example, speaker 133 may play instructions foroperating case 100, administering a medicament 120, or performing otheremergency care. Speaker 133 may also output live instructions or otheraudio provided by the remote operator. In various embodiments, such asthose embodiments to be deployed in noisy environments, the case mayinclude one or more sets of headphones (not shown) in addition to, or inplace of, speaker 133.

Display 134 may be an electronic display capable of showing video orimages. For example, display 134 may be a liquid crystal display (LCD)or other computer monitor. Display 134 may display instructions or otherinformation to a user such as video, images, and/or text demonstratingproper medication administration and/or emergency care. Such video,images, and/or text may be stored locally or transmitted from a remotelocation by a remote operator. Further, the video, text, and images maybe displayed as part of a scripted sequence stored locally or at theinstruction of a remote operator. For example, the remote operator maydisplay a next image in a sequence once the operator has verified that astep associated with a currently-displayed image has been properlyperformed, may display a video that the operator has identified asrelevant to a particular situation, or may type text for display to ahearing-impaired user. In various embodiments, display 134 may be atouch-screen display. A touch-screen display may be used as both adisplay and input device. Case 100 may also include an additional inputdevice 138 such as a keyboard, keypad, mouse, and/or other known inputdevices. Display 134 or input device 138 may be used to enterinformation into case 100. For example, an authorized user may enter asecurity code for accessing case 100 or receiving information from case100. As another example, a hearing-impaired user may type text messagesthat are subsequently transmitted to the remote operator. In variousalternative embodiments, the display or input device may be locatedinside a first door of the storage device, separated from the medicamentcompartment by a second door, drawer or other medicament lock. A userwould then open the first door to access the input device or display.

Card reader 135 may be a magnetic stripe reader for reading informationfrom a card. For example, authorized users, such as patients andemergency caregivers, may be issued a card providing access to thestorage case 100 along printed, electronically-stored, and/ormagnetically stored prescription and/or patient information, such aspatient records or a patient identifier. The card may be used to quicklyinput the user and/or patient information into case 100. Other types ofcard readers may include smart card readers, bar code scanners, quickresponse (QR) code scanners, or other devices for reading a token thatidentifies an individual.

Wireless reader 140 may be a device for reading and transmitting datavia radio frequency identification (RFID), near field communication(NFC), Bluetooth, or other short range wireless communications. Wirelessreader 140 may interact with wireless tags or devices located with case100 or external to case 100. Internal wireless tags or devices may beincluded as part of the medicaments 120. As will be described in furtherdetail below, medicaments 120 may include wireless tags that includeinformation regarding the medicament. Wireless reader 140 mayperiodically poll the tags to acquire information regarding themedicaments. For example, the wireless reader 140 may read an expirationdate from a tag carried by each medicament or may communicate with aseparate processor of each medicament (as will be described in greaterdetail below) to retrieve a Boolean value indicating whether themedicament is currently expired. If a medicament 120 is expired, thecase 100 may subsequently prevent the corresponding lock 122 fromopening under any or most conditions and/or transmit a message, such asa message to the remote operator, that the medicament is expired andshould be replaced.

External wireless tags may include identification cards of authorizedusers or patients. An RFID or NFC identification card may performsimilar authorization functions to cards using card reader 136 asdiscussed above, either in addition to or as an alternative to the cardreader 136. External wireless devices may include devices such as smartphones or other portable electronics. External wireless devices mayinclude applications for monitoring medicament usage or providing accessto case 100. Case 100 may provide information to an external wirelessdevice via wireless reader 140.

Various additional means for confirming an identity of a user will beapparent. For example, the storage case 100 may include devices (notshown) for retrieving biometric data for a user. As such, the storagecase 100 may include a fingerprint scanner, retina scanner, or otherbiometric information retrieval device. Additionally, or alternatively,the storage case 100 may retrieve a biometric-encoded password via theinput device 138. Upon retrieving an identifier for a user, such as anid string from a magnetic stripe or wireless communication chip or an idcalculated from biometric data, the storage case 100 may transmit the IDto a remote operator and/or retrieve user authorization data or otheruser information. For example, the storage case 100 may locally storeuser information or may communicate with a remote database to retrievethe appropriate user information.

In various embodiments, the case 100 or a portion thereof may be climatecontrolled. For example, the case 100 may include a refrigeratedcompartment for storage of medicaments for administration of insulin. Asanother example, the case 100 may include devices for controlling theinternal humidity, internal temperature and/or other climate conditions.Additional climate control devices will be apparent, including theappropriate sensors for measuring and reporting climate conditions.

FIG. 2 illustrates a schematic diagram 200 of the components of case100. Schematic diagram 200 includes lock 106, camera 130, microphone132, speaker 133, display 134, card reader 136, input device 138,wireless reader 140, actuator 210, sensors 220, communication unit 230,and global positioning system (GPS) receiver 240. Although not shown,the case 100 may include additional components such as a processor,memory, and/or storage device. Alternatively, such components may beincluded as part of and/or shared between those components that areillustrated. As used herein, the term “processor” will be understood toencompass various processing devices such as microprocessors,application-specific integrated circuits (ASICs), field-programmablegate arrays (FPGAs), and other processors. If included as a separatecomponent, a processor (not shown) may interconnect the variouscomponents illustrated in FIG. 2.

Actuator 210 may be coupled to lock 106 such that actuator 210 may movelock 106 between a locked position and an unlocked position. Actuator210 may receive a locally provided access signal from card reader 136,input device 138, wireless receiver 140, and/or a processor (not shown).The locally provided access signal may cause actuator 210 to unlock case100 without prior communication to a control center.

Sensors 220 a and b may provide monitoring of medicaments 120. Eachmedicament 120 may be equipped with a sensor 220. The sensor 220 may beintegrated into a medicament lock 122. In various embodiments, sensors220 may detect removal of the corresponding medicament 120 and providean indication to communication unit 230. Communication unit 230 mayreport the removal of the medicament 120 to a control center. In variousembodiments, sensors 220 may be implemented with wireless reader 140.Wireless reader 140 may periodically poll wireless tags attached to themedicament to collect information. Wireless reader 140 may determine ifa medicament 120 has moved out of the wireless range or if themedicament 120 provides other key information such as expiration of themedicament. In various embodiments, the sensors may be further adaptedto enable communication with one or more processors integrated into themedicaments 120.

The communication unit 230 may facilitate a two-way communication with acontrol center and provide a remote access signal from the controlcenter. The communication unit 230 may include any device forcommunicating information from the case 100 to the control center suchas a telephone or digital modem. Communication unit 230 may use wired(such as a phone line, Ethernet, or wired Internet connection) orwireless (such as wifi, mobile carrier network, or satellite)communication channels to communicate with the control center. Thecommunication unit 230 may be in communication (such as directly or viaa processor) to camera 130, microphone 132, speaker 133, and display 134to provide a live audio/video communication session between a user ofcase 100 and an operator at the control center. The operator at thecontrol center may gather information from and provide instructions to auser at the case 100. If the operator determines that access should beprovided to a medicament, the operator may provide a remote accesssignal via the communication unit 230. The communication unit 230 mayalso provide any other information gathered by the components of case100 to the control center. For example, a temperature sensor componentof case 100 may send an alert to the control center that the internaltemperature of the case is out of range and requires correction. Thecontrol center may then correct the temperature by use of thecommunication unit 230.

GPS receiver 240 may determine a physical location of case 100. Invarious embodiments, GPS receiver 240 receives signals from GPSsatellites in order to calculate a location of case 110. In variousalternative embodiments, GPS receiver 240 may include a memory forstoring a location such that active communication with GPS satellites isnot necessary. GPS receiver 240 may provide the location information tocommunication unit 230 so that it may be forwarded to a control center.

FIG. 3 illustrates an exemplary electronic medicament device 300. Theelectronic medicament device 300 may include a medication for treating acondition, the medication being stored in a reservoir. In variousexemplary embodiments, the electronic medicament device 300 includes anauto-injector for epinephrine or other administration component such asa non-auto-injector needle or controlled access panel for providingaccess to a solid medication stored in the reservoir. The electronicmedicament device 300 may further include sensor 310, ID tag 320, memory330, display 340, and speaker 350. Although not illustrated, theelectronic medicament device may include additional hardware such as,for example, a processor and/or additional communication interfaces. Aprocessor may interconnect one or more of those components illustratedin FIG. 3. Such additional communication interface may include, forexample, an interface for communication via wifi, a mobile carriernetwork, or satellite. Alternatively, the additional communicationinterface may include a wired communication interface.

Sensor 310 may detect activation of electronic medicament device 300.Sensor 310 may include a frangible element that completes or breaks anelectronic circuit when electronic medicament device 300 is activated.Sensor 310 may provide a signal to ID tag 320 to perform an action inresponse to use of the medicament. Sensor 310 may alter memory 330 toindicate that the medicament device 300 is used and may log a time ofuse.

ID tag 320 may include an RFID, NFC, or other tag for short rangewireless communications. Such tags may be powered by passive energy andnot require a battery. In various embodiments, ID tag 320 may include abattery powered wireless transmitter using, for example, Bluetooth. IDtag 320 may provide information from electronic medicament device 300 toa wireless reader such as, for example, wireless reader 140 or a NFCenabled mobile device. ID tag 320 may be connected to or include memory330.

Memory 330 may store information regarding electronic medicament device300. Memory 330 may include a non-volatile memory such as a read-onlymemory (ROM) or an electronically erasable programmable read only memory(EEPROM). Information stored by memory 330 may include manufacture date,expiration date, medication, dose size, audio instructions, textinstructions, other instructions, prescription information, re-orderinformation, and emergency contact information.

Display 340 may include a display such as a LCD, LED array, or a singleLED. Display 340 may display information about electronic medicamentdevice 300. Display 340 may read and display any information stored inmemory 330. For example, display 340 may display the expiration date ofthe medication. Display 340 may also display instructions for a user. Invarious embodiments, display 340 may illuminate, flash, or display aparticular message in response to particular events such as theexpiration of the medication, use of the medicament, or separation fromanother device such as case 100 or a mobile device.

Speaker 350 may provide audio output. For example, speaker 350 may playpre-recorded instructions stored in memory 330. In various embodiments,ID tag 320 or another communication interface (not shown) may downloador stream information from another device to be played by speaker 350.For example, the electronic medicament device 300 may stream informationfrom a storage case 100 or from a remote operator, either directly orvia a storage case 100.

Various functions described above in connection with the storage case100 may be provided directly on the electronic medicament device 300.For example, the electronic medicament device may include a microphonefor transmitting audio to a remote operator, a GPS device fordetermining a current location, a keypad for inputting an authorizationcode, or any of the other components described above in connection withthe storage case. As such, the electronic medicament device 300 may beprovided and used in contexts that do not involve the storage case 100.For example, a physician or pharmacy may provide the electronicmedicament device 300 directly to a patient for future use.

In various embodiments, the electronic medicament device 300 may bereusable. As such, the electronic medicament device 300 may receive adisposable cartridge or component set including the medication and/or aclean needle. Such cartridge or component set may include its own RFIDtag or other means for communicating an expiration date or otherinformation to the electronic medicament device 300 or a storage case100.

In various embodiments, the processor or other component of theelectronic medicament device 300 may alter the operation of theelectronic medicament device 300 based on user information or otherinformation. For example, the electronic medicament device 300 mayprovide different dosages based on a dosage prescribed to an authorizeduser. As another example, a user may input a patient weight into akeypad of the electronic medicament device 300. The processor may thencalculate and administer an appropriate dosage based on the inputweight. As another example, the processor may prevent or disablemedicine administration when the user is not authorized for suchadministration.

FIG. 4 illustrates an exemplary network environment 400 for storage case100 and electronic medicament device 300. Storage case 100 andelectronic medicament device 300 may interact with various elements ofnetwork environment 400 to provide emergency access and enhancedfeatures. Network environment 400 includes network 405, GPS satellites410, mobile device 420, mobile base station 425, wireless router 430,medical server 440, central control 450, and emergency services 460.

Network 405 may be a digital network for communicating information. Forexample, network 405 may be the internet. Network 405 may transmitinformation between various end users and devices. Network 405 may alsoinclude telephone networks.

GPS satellites 410 may enable storage case 110, electronic medicamentdevice 300, mobile device 420, and other devices to determine theirrespective physical locations. GPS satellites 410 may be geosynchronoussatellites that broadcast signals. GPS enabled devices may use thesignals from multiple satellites to determine their location. In variousembodiments, GPS satellites 410 may include or be replaced byterrestrial location systems.

Mobile device 420 may be a device such as a smart phone, tabletcomputer, laptop, or any other computing device capable of executingapplications and performing communication. In various embodiments,mobile device 420 is an NFC enabled mobile phone that can communicateusing short range wireless protocols as well as local networking andmobile networks. In particular, mobile device 420 may communicate with amobile network using mobile base station 425.

Mobile device 420 may interact with the storage case 100 and/or theelectronic medicament device 300 using RFID, NFC, or other wirelesscommunication. For example, the mobile device 420 may transmit a useridentification to the storage case 100 or the electronic medicamentdevice 300 for authorizing the holder of the mobile device 420 to accessand/or administer the electronic medicament device. The mobile device420 may automatically transmit the user identification, such ascontinuously or periodically, such that the user may be easilyauthorized in an emergency situation. In various alternativeembodiments, the mobile device 420 may only transmit the useridentification upon request by the user. Mobile device 420 may also actas an interface for accessing the storage case 100 and/or electronicmedicament device 300. For example, mobile device 420 may allow forcommunication between the user and control center, thereby facilitatingdiagnosis if the user is not movable.

Mobile device 420 may include an application specifically forinteracting with electronic medicament device 300. Mobile device 420 mayaccess memory 330 via ID tag 320 and read or write data. Mobile device420 may detect changes in electronic medicament device 300 and performactions in response. For example, mobile device 420 may detect thatelectronic medicament device 300 has been activated. Mobile device 420may automatically contact emergency services 460 and allow a user tospeak with emergency personnel, or mobile device 420 may provide apre-recorded message to emergency services 460 indicating that themedicament has been activated to treat a condition of the patient.Mobile device 420 may also provide a location based on GPS informationso that emergency personnel can locate the patient.

ID tag 320 may be used to determine whether electronic medicament device300 is within close proximity to a mobile device 420. ID tag 320 mayperiodically poll or be polled by a wireless reader in the mobile device420. If the poll does not occur when expected, or the mobile device doesnot respond, electronic medicament device 300 may generate an alert. Forexample, electronic medicament device 300 may play a sound through thespeaker 350 or flash the display 340 to alert a user. The alert mayremind the user to keep the medicament close by in case of emergency.Mobile device 420 may also generate an alert if electronic medicamentdevice 300 is not detected. Mobile device 420 may be configured to checkfor the presence of electronic medicament device 300 whenever the userenters or leaves a particular location. For example, mobile device 420may generate an alert if a user leaves home without the electronicmedicament device.

Mobile device 420 may also contact emergency contacts. For example,mobile device 420 may email, message, or call any emergency contactsstored in memory 330 or within mobile device 420 when the electronicmedicament device 300 is used or generates some other alert. Mobiledevice 420 may select contacts based on time of day or other availableinformation.

Upon detection of an expired medicament or activation of the medicament,mobile device 420 may initiate ordering a replacement medicament Mobiledevice 420 may send an order to either control center 450 or medicalserver 440. The order may include patient and prescription information.Medical server 440 may determine whether the prescription includesrefills, whether replacements are allowed without a prescription, orwhether the patient has a valid or perpetual prescription for themedicament. Medical server 440 may automatically fulfill the order ifthe prescription is authorized. Alternatively, medical server 440 mayschedule an appointment with the patient's doctor for a new prescriptionand to follow-up regarding the deployment of the medicament.

Wireless router 430 may be a wireless router providing connectivity to alocal area network (LAN) and the internet. Wireless router 430 may beaccessed by storage case 100, electronic medicament device 300, andmobile device 420. Accordingly, wireless router 430 may provide thesedevices with internet access to send and receive data.

Medical server 440 may be a server operated by a health care provider orhealth insurance provider. Medical server 440 may store patientinformation. Medical server 440 may provide patient information toauthorized devices such as the patient's mobile device 420, controlcenter 450, and emergency services 460. Medical server 440 may beconfigured to receive and process particular messages from storage case100, electronic medicament device 300, mobile device 420, and controlcenter 450. For example, medical server 440 may be configured to verifyprescriptions and order refills.

Control center 450 may include a server that communicates with one ormore storage cases 100, electronic medicament devices 300, and/or mobiledevices 420. Control center 450 may include an operator interface thatallows an operator located at or in communication with control center350 to communicate with a patient at a storage case 100. The controlcenter may facilitate a two-way audio and/or video communication sessionbetween a user or patient at the storage case 100 and the operator. Theoperator may be able to diagnose the patient based on the two-waycommunication. The control center 450 may also receive information fromstorage case 100 such as available medicaments and location. If anoperator of control center 450 determines that a medicament should beadministered to a patient, control center 450 may generate a remoteaccess signal to unlock storage case 100.

The control center 450 may communicate with medical server 440 to obtainmedical information, such as prescriptions, regarding a patient. Thecontrol center 450 may communicate with emergency services 460 toprovide patient information to emergency personnel. Additionally, thestorage case 100 and/or electronic medicament device 300 may retrievevarious user information from the medical server 440, the control center450, or from other servers (not shown). For example, the storage casemay retrieve patient records from the medical server 440 and userpermissions from the control center 450.

It will be apparent that various additional devices may participate inexemplary network 400. For example, exemplary network 400 may includeone or more servers for providing an application service to a user. Forexample, the electronic medicament device 300 may provide usageinformation to such an application server which, in turn, may processthe data for various uses. For example, the application server may thenprovide the processed usage data to an application executing on a mobiledevice, such as mobile device 420. Such application may provide, forexample a map indicating where the user has administered the electronicmedicament device 300 and/or other electronic medicament devices 300.Such application could also present a real-time alert as to when theelectronic medicament device 300 has been used, including locationinformation. The application may also provide historical data andanalysis of electronic medicament device 300 usage events such as eventlistings and graphs.

FIG. 5 illustrates a flowchart showing an exemplary method 500 ofproviding remote access to a medicament. The method 500 may be performedby a control center 450. The method 500 may begin at step 510 andproceed to step 515.

In step 515, the control center 450 may receive a communication requestfrom a remote medicament storage case 100. The control center 450 maydetermine an operator who is available to communicate with a potentialpatient. In step 520, the control center 450 may establish a two-waycommunication session between the selected operator and the remotestorage case 100. In step 525, the control center 450 may also receivelocation information from the remote storage case 100. In step 530 thecontrol center 450 may access a medical record of the patient based onan identifier provided to the operator by the patient through thetwo-way communication session or by the storage case 100 electronically.The patient may be identified using a card scanned at the storage case100 or using the patient's name or other identifying information. Themedical record may be retrieved from an internal database or may beprovided by a medical server 440. In step 535, control center 450 mayreceive input of the patient's condition from the operator.Alternatively, the condition may be input at the storage case andapproved by the operator. In step 540, control center 450 may transmitthe patient's condition along with other information such as thepatient's identity and location to emergency services 460. Emergencyservices 460 may be selected according to proximity to the patient.Control center 450 may also notify other emergency contacts if availablefrom the patient's medical record or information received at the storagecase. In step 545, control center 450 may determine the contents of thestorage case 100. Control center 450 may receive a list of medicamentsfrom the storage case 100. In step 550, control center 450 may determinewhether the remote storage contains a medicament for the condition ofthe patient. Control center 450 may include a list of rules forcomparing conditions and medicaments. Alternatively, the operator maydetermine whether any medicament is appropriate for treating thepatient. If a medicament is available, the method 500 may proceed tostep 550. If no medicament is available, the method 500 may proceed tostep 565. In step 555, the control center 450 may transmit an accesssignal to storage case 100. The access signal may unlock the storagecase 100 and/or a medicament lock 106 for the medicament. In step 560,the control center 450 may transmit instructions for administering themedicament. The instructions may be provided by the operator or may bepre-recorded instructions specific for the medicament. If the storagecase 550 does not include an appropriate medicament, in step 565, thecontrol center 450 may provide any relevant first aid instructions forthe patient's condition. Control center 450 may maintain thecommunication session until emergency personal have arrived to assistthe patient. The method may then proceed to step 570, where the methodends.

FIG. 6 illustrates a flowchart showing an exemplary method 600 ofmonitoring a medicament. The method 600 may be performed by a mobiledevice 420 in communication with an electronic medicament device 300.

The method 600 may begin at step 605 and proceed to step 610. In step610, the mobile device 420 may determine its location. In variousembodiments, mobile device 420 may use the location to determine whetherto proceed with the method. For example, the mobile device 420 maydiscontinue the method if the mobile device is in a designated location,or the mobile device may delay the method until a change in location isdetected.

In step 615, the mobile device 420 may detect any electronic medicamentdevices nearby. Mobile device 420 may use RFID, NFC, Bluetooth oranother close range protocol to poll nearby tags on a medicament device.Mobile device 420 may be configured to poll one or more specificelectronic medicament devices with identifiers known by mobile device420. In step 620, mobile device 420 may determine whether an electronicmedicament device is present. If no medicament device is present, themethod may proceed to step 625. If a medicament device is detected, themethod may proceed to step 630.

In step 625, the mobile device 420 may generate an alarm. The alarm mayindicate any particular medicament device that was not detected. Thealarm may include a message identifying the medicament device by name orby a condition that it treats. If the mobile device performs method 600frequently, it may be likely that the medicament device is nearby,although out of range of the short range wireless protocol. Accordingly,a user may be reminded to retrieve the medicament device. The method maythen proceed to step 660, where the method ends.

In step 630, the mobile device 420 may receive data from the medicamentdevice. Mobile device 420 may send a read command to read data frommemory 330. In various embodiments, mobile device 420 may receive datafrom the electronic medicament device 300 when sensor 310 determinesthat the device 300 has been activated. In step 635, mobile device 420may determine whether the medicament device 300 has been used. Mobiledevice 420 may determine the status of sensor 310 or parse data receivedin step 630. If the medicament device has been used, the method mayproceed to step 640. If the medicament device has not been used, themethod may proceed to step 650.

In step 640, mobile device 420 may document the current location of themobile device. In step 645, the mobile device may notify emergencycontacts. Mobile device 420 may contact emergency services, for example,by dialing 911. The mobile device 420 may turn on a speaker phone toallow a user, who may be suffering from anaphylaxis or another medicalcondition to speak to an emergency dispatcher. If mobile device 420 doesnot receive any voice input, mobile device 420 may play a recordedmessage indicating that the electronic medicament device has beenactivated at the stored location. Mobile device 420 may also contactother people. For example, mobile device 420 may call, email, or messageemergency contacts stored in mobile device 420 or memory 330.

In step 650, mobile device 420 may determine whether the electronicmedicament device is expired. Mobile device 420 may compare anexpiration date received from the electronic medicament device 300 tothe current date. If the medicament device is expired, the method mayproceed to step 655. If the medicament device is not expired, the methodmay proceed to step 650, where the method ends.

In step 655, the mobile device 655 may initiate an order for a refill orreplacement electronic medicament device. Mobile device 420 may send anorder to control center 450 and/or medical server 440. The method maythen proceed to step 650, where the method ends.

According to the foregoing, various exemplary embodiments provide forsystems and methods for distributing medicaments. In particular, byproviding remote access to a medicament storage case, medicaments can beprovided to patients in an emergency.

It should be apparent from the foregoing description that variousexemplary embodiments of the invention may be implemented in hardwareand/or firmware. Furthermore, various exemplary embodiments may beimplemented as instructions stored on a machine-readable storage medium,which may be read and executed by at least one processor to perform theoperations described in detail herein. A machine-readable storage mediummay include any mechanism for storing information in a form readable bya machine, such as a personal or laptop computer, a server, or othercomputing device. Thus, a machine-readable storage medium may includeread-only memory (ROM), random-access memory (RAM), magnetic diskstorage media, optical storage media, flash-memory devices, and similarstorage media.

It should be appreciated by those skilled in the art that any blockdiagrams herein represent conceptual views of illustrative circuitryembodying the principals of the invention. Similarly, it will beappreciated that any flow charts, flow diagrams, state transitiondiagrams, pseudo code, and the like represent various processes whichmay be substantially represented in machine readable media and soexecuted by a computer or processor, whether or not such computer orprocessor is explicitly shown.

Although the various exemplary embodiments have been described in detailwith particular reference to certain exemplary aspects thereof, itshould be understood that the invention is capable of other embodimentsand its details are capable of modifications in various obviousrespects. As is readily apparent to those skilled in the art, variationsand modifications can be affected while remaining within the spirit andscope of the invention. Accordingly, the foregoing disclosure,description, and figures are for illustrative purposes only and do notin any way limit the invention, which is defined only by the claims.

1-25. (canceled)
 26. A medicament device comprising: a structureconfigured to receive an epinephrine auto-injector; a wirelesscommunication device configured to wirelessly communicate informationwith a mobile device, wherein the information allows for determiningwhether the medicament device is within close proximity to the mobiledevice; a processing device configured to: determine that theepinephrine auto-injector is associated with a designated user of theepinephrine auto-injector, and in response to the medicament device notbeing within close proximity to the designated user of the epinephrineauto-injector, perform at least one of (i) causing a display on themedicament device to illuminate or (ii) causing a sound source on themedicament device to plays a sound.